Our Methodology

Clinical sources, not gimmicks

Every finding is traced to established clinical databases. We present the evidence, not opinions. Our methodology blends clinical genomics with herbal medicine traditions.

How It Works

Three steps from raw data to insight

1
Genomics

Upload & Parse

Upload your raw genotype file from any major consumer service. Your browser parses it entirely locally — your full genomic file, the physical artifact that could forensically re-identify you, never leaves your device. Our system works solely from your individual findings, which are common across large portions of the population and cannot be reassembled into a person's identity.

2
Clinical

Variant Analysis

Your variants are matched against peer-reviewed clinical databases maintained by leading research institutions. Each match is annotated with pathogenicity classifications, drug-gene interactions, and evidence levels.

3
Pharmacogenomics

Narrative Generation

Structured findings are processed through the DNA Health Insights report framework, where AI assistance helps draft plain-language education under source rules, safety boundaries, and report-structure constraints.

We never transmit your full genomic file

Our privacy promise is drawn at a precise boundary: your full genomic file — the artifact that could forensically re-identify you — remains entirely under your control and never leaves your device. All parsing and variant matching happen locally in your browser, with no server uploads or cloud storage for the raw file. Our system works solely from your individual structured findings, which represent common traits shared by large portions of the population and cannot be reassembled into a person's identity. Only these non-identifying findings are shared with our narration service to translate results into clear, plain language, ensuring your report is highly accurate while keeping your identity completely secure.

Data Sources

Scientific rigor, source-agnostic

Our analysis is powered by multiple independent, government-backed research databases. We cross-reference your genetic variants against clinically validated research from established institutions. All our data sources are public domain or openly licensed, ensuring that our findings are based on the highest standards of transparency and accessibility.

Clinical

Clinical Variant Databases

We utilize curated archives of clinically significant genetic variants. These databases contain millions of pathogenicity classifications used by clinical labs worldwide, maintained by leading government and research institutions.

Clinically Validated
Pharmacogenomics

Curated Drug-Gene Evidence

Our analysis compares your genetic findings with drug-gene evidence curated by ClinPGx scientists from peer-reviewed research. This NIH-funded clinical pharmacogenomics resource helps explain how genetic variation has been studied in relation to medication response.

Evidence-Based

Our Commitment to Transparency

  • We attribute sources through published research citations rather than database brands, focusing on the underlying science.
  • Our system is designed to be modular, allowing us to incorporate new research databases as they become available to ensure you always have the latest insights.
  • Every finding in your report is traceable to peer-reviewed research and validated clinical data.
Genomics

Nutritional Reference Data

Metabolic traits, caffeine response, and nutrient needs based on national nutritional reference data.

Clinical

Variant Data

Inherited conditions, carrier status, and risk factors derived from clinical variant databases.

Pharmacogenomics

Drug-Gene Research

ClinPGx-curated evidence about how genetic variation has been studied in relation to medication response.

Interpretive framework and report compilation methodology developed for DNA Health Insights, with technical implementation by Mastermind Group Ventures LLC.